Therapeutic Drug Monitoring

A target vancomycin trough concentration range of 10 to 15 mg/L for adults is recommended. • Target vancomycin trough concentrations between 15-20 mg/L are ...

In this article: · Maintain trough serum vancomycin concentrations of at least 10 mg/L for all infections to avoid the potential for resistance · Maintain ...

When to draw levels: Trough: just before 4th dose of a new regimen (prior to 3rd dose for dosing intervals ≥ 24 hours or changing renal function).

Initial: A single level should be drawn within the first 24-48 hours after the first dose. i. An earlier initial level may be helpful in ...

Vancomycin serum trough concentrations of 15–20 mg/L are recommended to improve penetration, increase the probability of obtaining optimal target serum ...

Trough levels should be maintained above 10mg/L to avoid resistance . The usual target range for vancomycin is 10-15mg/L. For MRSA pneumonia, osteomyelitis, endocarditis and bacteraemia the target trough levels are 15-20mg/L to improve penetration to

These consensus guidelines recommend an AUC/MIC ratio of 400–600 mg*hour/L (assuming a broth microdilution MIC of 1 mg/L) to achieve clinical efficacy and ...

Give loading dose 20 mg/kg over 1 hour, followed by continuous infusion; Usual starting dose for continuous infusion is 60 mg/kg/day. Switching from ...

If CrCl is less than 20mL/min check trough level 24 hours after loading dose; wait for trough to fall below 20mg/L prior to re-dosing. To ...

Typically 15 to 20 mg/kg every 8 to 12 hours for most patients (based on actual body weight, rounded to the nearest 250 mg increment). In general, the approach ...